All of Messi's Matches Against Paraguay: 2005: 0-1 vs. Paraguay in Asunción (2006 World Cup Qualifiers) 2007: 1-0 vs. Paraguay in Copa América; 2008: 1-1 vs. Paraguay in Buenos Aires (2010 World Paraguay vs. Argentina puts Messi against Inter Miami teammate. The match also puts a spotlight on Paraguay's Diego Gomez, the No. 1 player on the MLS 22 under 22 list from this season and Messi Sports Mole goes back through the archives to take a look at Lionel Messi's record against Paraguay in the blue and white of Argentina. The Argentinian legend has come up against La Albirroja 13 Paraguay 2, Argentina 1. Omar Alderete (Paraguay) header from the right side of the six yard box to the top left corner. Assisted by Diego Gómez with a cross following a set piece situation. Argentina can move even closer to a spot at the World Cup by beating Paraguay and Peru. Captain Lionel Messi will be his team's best hope for goals once again after his hat trick and two assists in the 6-0 win against Bolivia in October, with the 37-year-old the top scorer in the current South American qualifying. Argentina are back in action on Thursday with a trip to Asuncion to face a tough Paraguay test with a chance to inch closer to a FIFA 2026 World Cup berth. Lionel Messi and company saw off Bolivia Lionel Messi's Argentina fell 2-1 to Paraguay in Matchday 11 of the 2026 World Cup Qualifiers at Defensores del Chaco stadium. Paraguay came back from Lautaro Martinez's early goal to defeat Lionel Messi earns a record-equalling 147th cap for Argentina as they progress to the Copa America quarter-finals with victory over Paraguay. After a foul by Paraguay's Gustavo Gómez, Messi's free kick bounces off the left post and away from the goal (90 +3'). Argentina goalkeeper sets new national team record Argentina ensured their place in the Copa America quarter-finals on Monday when they beat Paraguay 1-0 as Lionel Messi made a record-equalling 147th appearance for the national side.